Quiescent or Senescent? Cancer Center 91��Ҹ� Helps Identify Cancer That is More Likely to Recur

Jessica Helzer — Mon, 16 Feb 2026 13:27:53 +0000

Quiescent or Senescent? Cancer Center 91��Ҹ� Helps Identify Cancer That is More Likely to Recur Jessica Helzer Mon, 02/16/2026 - 06:27

Associate professor Sabrina Spencer, PhD, and PhD candidate Brianna Fernandez led the study published in Nature Communications.

In a study that could have implications for more effective cancer therapies and preventing cancer recurrence, 91��Ҹ� Anschutz Cancer Center member Sabrina Spencer, PhD, working with graduate student Brianna Fernandez, used single-cell RNA sequencing to investigate the cell-cycle state of cells following chemotherapy.

Specifically, the researchers were looking to characterize cells in one of two arrested states: quiescence, a reversible state of cell-cycle arrest, and senescence, an irreversible state of cell-cycle arrest. Their research was published in January 2026 in the journal Nature Communications.

The Department of Biochemistry at CU 91��Ҹ� looks forward to the ongoing Spencer/Fernandez research and what the duo will continue to discover.

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Associate professor Sabrina Spencer, PhD, and PhD candidate Brianna Fernandez

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Brianna Fernandez

Quiescent or Senescent? Cancer Center 91���Ҹ� Helps Identify Cancer That is More Likely to Recur

Associate professor Sabrina Spencer, PhD, and PhD candidate Brianna Fernandez led the study published in Nature Communications.

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Quiescent or Senescent? Cancer Center 91��Ҹ� Helps Identify Cancer That is More Likely to Recur